Starting Your Weight Loss Journey: The First 90 Days on Injectable Therapy

Are you considering injectable medication for weight management? When you get Mounjaro for weight loss or similar treatments, knowing what's ahead can make your journey smoother. 

In this guide, we'll walk you through what to expect during your first 90 days, from initial adjustments to potential results.

Before You Begin: Setting Realistic Expectations

Starting injectable weight management therapy is a significant step. Your healthcare provider should be your primary source of information throughout this process. 

They'll consider your medical history, current health, and weight goals before prescribing any medication.

Remember that these medications work best when combined with healthy eating and regular physical activity. They're tools to help you—not magic solutions.

Week 1: The Adjustment Period

Your first week will likely involve getting comfortable with the injection process and your new routine. Don't worry if you're nervous about self-injecting—most people quickly overcome this fear.

Many patients report feeling different almost immediately, though not necessarily in weight. You might notice:

• Reduced hunger sensations

• Feeling full faster during meals

• Less interest in snacking between meals

Common First-Week Side Effects

Side Effect	Typical Severity	Management Tips
Nausea	Mild to moderate	Take medication as prescribed, eat smaller meals
Fatigue	Mild	Ensure adequate rest, stay hydrated
Injection site reactions	Mild	Rotate injection sites, follow proper technique

During this first week, focus on staying hydrated and listening to your body. Side effects are most common when starting treatment and often improve with time.

Weeks 2-4: Establishing Your Routine

By now, the injection process should feel more familiar. Your body is adapting to the medication, and you might start seeing small changes on the scale.

This is when many people report their appetite regulation becoming more noticeable. You may find yourself:

• Naturally choosing smaller portions

• Having fewer cravings for high-calorie foods

• Feeling satisfied longer after eating

It's important to work with the medication rather than against it. Eat when you're hungry, stop when you're full, and choose nutrient-dense foods that support your health.

Months 1-2: Seeing Initial Results

Most people start seeing measurable results during this period. Research shows patients typically lose about 5-10% of their body weight within the first three months, though individual results vary greatly.

This is often when motivation peaks as the effects become visible. You might notice:

• Clothes fitting differently

• Improved energy levels

• Better sleep quality

• Changes in how others respond to you

Remember that weight loss isn't linear—some weeks you'll lose more than others, and that's completely normal. The key is consistency with your medication schedule and healthy habits.

The Third Month: Adjusting to Your New Normal

By your third month, the routine of medication, healthy eating, and physical activity should feel more natural. Your provider might consider adjusting your dosage based on your progress and side effect profile.

What to Watch For During Month Three

Positive Signs	Areas of Concern
Sustainable weight loss pace	Plateau that lasts more than 2 weeks
Minimal side effects	Severe or worsening side effects
Improved lab results	Unusual symptoms
Better energy levels	Excessive fatigue or weakness

Always communicate openly with your healthcare provider about how you're feeling. This helps them determine if you need dosage adjustments or additional support.

Beyond the First Three Months

Most injectable weight management therapies are designed for longer-term use, often 6-12 months or more. Your first three months lay the foundation for your continued success.

"The initial three months on injectable therapy are just the beginning of your weight management journey. Maintaining the habits you develop during this time significantly improves your chances of long-term success."

Final Thoughts

Starting injectable weight management therapy can be life-changing when approached with the right expectations and support.

The first three months are about more than just weight loss—they're about establishing sustainable habits that support your health goals.

Remember that your experience with medications like Mounjaro may differ from others. What matters most is how the treatment works for you and your unique body.